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KMID : 0359719950130020362
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Journal of the Korean Neurological Association
1995 Volume.13 No. 2 p.362 ~ p.366
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A Case of Myasthenia Gravis Associated with Premature ovarian Failure and Thyroid Autoanibodies
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함동석
장세희/윤영철/김우정/권오상/박형무/김두웅/이광우
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Abstract
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Myasthenia gravis (MG) is regarded as auteimmune disorder of neuromuscular transmission and apparently is due to formation of humoral antibody that cross-link to acetylcholine receptor at skeletal muscle end plate. Patients with autoimmune
diseases
often have circulating antibodies to a variety of different autoantigens and show a variety of manifestations of autoimmune disease in more than one organ. Therefore, MG patients frequently have manifestations of autoimmune diseases such as
thyroid
disease, rheumatoid arthritis and systemic lupus erythematosus. But aMG in association with premature ovarian failure (POF) rarely has been deseribed.
A case of MG with POF and thyroid autoantibodies was experienced and presented with a brief review of literature.
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